Related Experiment Video
Updated: May 7, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
[Use and limitations of invasive coronary strategy in nonagerians]
J-L Georges1, B Jerbi, G Gibault-Genty
1Service de cardiologie, hôpital André-Mignot, centre hospitalier de Versailles, 177, rue de Versailles, 78157 Le Chesnay cedex, France.
Insights
Coronary angiography and intervention are feasible and safe in nonagenarians, offering a high success rate with acceptable complication risks. These procedures provide valuable diagnostic and therapeutic options for this understudied elderly population.
Area of Science:
- Interventional Cardiology
- Geriatric Cardiology
- Vascular Interventions
Context:
- Nonagenarians (≥90 years) are often excluded from cardiovascular studies.
- Limited data exist on the safety and efficacy of coronary angiography (CA) and percutaneous coronary intervention (PCI) in this extreme age group.
Purpose:
- To evaluate the benefits and hazards of CA and PCI in nonagenarians.
- Assess the feasibility, success rates, and complication profiles of these procedures in patients aged 90 and above.
Summary:
- A retrospective study analyzed 107 CA/PCI procedures in 97 nonagenarians (median age 92) from 2001-2011.
- Indications included acute coronary syndromes (77%); PCI success rate was 90%, with radial access used in 94% (2009-2011).
- Overall hospital mortality was 10%, with 19% experiencing severe complications, 11% directly procedure-related.
Impact:
- CA and PCI are feasible in nonagenarians, particularly via the radial approach, with manageable complication rates.
- PCI can be safely proposed to selected nonagenarian patients with acute coronary syndromes, demonstrating high success and acceptable risks.
- Findings support the consideration of advanced cardiac interventions in the very elderly, challenging previous exclusion criteria.
Background:
Nonagenarians are systematically excluded from studies of interventional cardiology. Few data exist on the usefulness, safety, and results of coronary angiography (CA) and percutaneous coronary intervention (PCI) in this population.
Purpose:
To evaluate the benefits and hazards of CA and PCI in nonagenarians.
Methods:
Retrospective study conducted from the database (Cardioreport(®)) of the CH de Versailles, from January 2001 to December 2011.
Results:
From the 15,806 procedures performed in the center during the period, 107 (0.9%) were done in 97 patients aged ≥90years. Half of them underwent PCI. Median age was 92±2years (range: 90 to 100), 56% were women. Main indication was an acute coronary syndrome (77%, acute STEMI in 39%). The first group (n=58) had a single CA leading to strengthen medical treatment, and CABG in one case. The second group (n=49) had a CA followed by immediate (41) or delayed (8) PCI. The primary success rate of PCI was 90%. Radial route was used in 94% in the period 2009-2011 (51% overall). Failure of arterial access (4%) and difficulties of catheterization (13%) were rare. Severe complications occurred in 19%. They were local (11 hematomas, 6 severe, 4 transfusions, and 1 fatal acute ischemia of a lower limb), and general (1 stroke, 1 death by left main rupture during PCI). Twenty percent of the complications (11% of severe ones) were directly related to the procedure. Overall hospital mortality was 10%.
Conclusions:
Angiography is feasible in nonagenarians by radial approach without failures and with a reduced rate of complications. PCI was indicated in about half of the cases. PCI may be proposed in nonagerians with a high success rate, and an acceptable risk of local and general complications.
More Related Videos
Related Concept Videos
Coronary Artery Disease IV: Preventive Measures
Coronary Artery Disease V: Interprofessional Care
Angina IV: Management
Angina II: Classification
Acute Coronary Syndrome IV: Interprofessional Care
Cardiac Catheterization I: Pre-Procedure Overview

