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Updated: May 7, 2026

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection
Published on: September 14, 2019
Cryptosporidium from a free-ranging marsupial host: bandicoots in urban Australia
Matthew Dowle1, Nichola J Hill, Michelle L Power
1Department of Biological Sciences, Macquarie University, North Ryde, Sydney, NSW 2109, Australia.
Abstract:
Expansion of human settlement has increased the interface between people and bandicoots with implications for the emergence and spread of zoonotic parasites. The host status of bandicoots inhabiting suburban areas and their potential role in Cryptosporidium transmission remains unresolved. Our study aimed to determine the prevalence and identity of Cryptosporidium in two sympatric bandicoot species. Cryptosporidium signatures were detected in twelve bandicoot faecal samples (n=98) through amplification of the 18S rRNA. Phylogenetic inference placed the isolates in a clade with Cryptosporidium parvum, a species with a broad host range and zoonotic potential, or loosely related to Cryptosporidium hominis. However, the identity of the bandicoot isolates was not fully resolved and whether they were infected or simply passively transmitting oocysts is unknown. This study revealed that free-ranging bandicoots of northern Sydney were shedding Cryptosporidium oocysts at a prevalence of 12.2% (95% CI [6.76, 20.8]), similar to marsupial species that act as reservoirs for Cryptosporidium. Our findings expand the range of hosts known to shed Cryptosporidium in urban areas.
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