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Updated: Aug 14, 2026

Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation
Published on: July 3, 2015
DNA adducts as markers of exposure in hazardous waste workers
M A McDiarmid1, P T Strickland
1Department of Environmental Health Sciences, Johns Hopkins University School of Hygiene and Public Health, Baltimore, Maryland 21205.
Abstract:
The interaction of a chemical or physical agent with DNA, resulting in the formation of covalent adducts or other modifications, has been implicated in the carcinogenic process for certain classes of chemicals. Demonstration of modified DNA may be taken as evidence of the interaction of a genotoxic agent with DNA, which is the basis for this review of DNA adducts as markers of exposure in hazardous waste work.
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