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Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
12:59

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

Published on: September 26, 2013

The Th17/Treg balance is disturbed during aging.

Vanessa Schmitt1, Lothar Rink, Peter Uciechowski

  • 1Institute of Immunology, Medical Faculty, RWTH Aachen University, Pauwelsstr. 30, D-52074 Aachen, Germany.

Experimental Gerontology
|September 24, 2013
PubMed
Summary

Aging alters immune cells, increasing pro-inflammatory T helper 17 (TH17) cells and decreasing regulatory T cells (Tregs). This imbalance in older adults may heighten susceptibility to inflammatory diseases.

Keywords:
AgingFoxp3IL-10IL-17Th17Treg

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