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Development of a Larval Zebrafish Infection Model for Clostridioides difficile
Published on: February 14, 2020
Codfish may cause acute abdomen.
Carlos E Costa Almeida1, Rui Rainho, António Gouveia
1ULS Castelo Branco, Cirurgia, Rua José Carlos Gomes Pita, n°2, 2° direito, 3040-193 Coimbra, Portugal.
Foreign body ingestion, particularly from fish bones, can cause rare but serious gastrointestinal perforations. Prompt diagnosis and surgical intervention are crucial for effective treatment of these challenging cases.
Area of Science:
- Gastroenterology
- Surgical Pathology
Background:
- Foreign body ingestion is common and can lead to severe gastrointestinal complications.
- Bowel perforation, though rare, is a significant risk associated with ingested foreign objects, with fish bones being a frequent culprit.
Purpose of the Study:
- To highlight the diagnostic challenges and management of gastrointestinal perforation secondary to foreign body ingestion.
- To emphasize the importance of clinical suspicion and diagnostic tools in identifying fish bone-related perforations.
Main Methods:
- Case presentation of a 77-year-old patient with severe abdominal pain.
- Diagnostic imaging utilizing CT scan to identify a foreign body and associated liquid collection.
- Surgical intervention involving laparotomy for abscess resection containing a fish bone.
Main Results:
- A fish bone was identified as the cause of a gastrointestinal abscess and perforation.
- Surgical resection of the abscess and foreign body was successfully performed.
Conclusions:
- Gastrointestinal perforation by foreign bodies, such as fish bones, can present as other abdominal emergencies, often leading to delayed diagnosis.
- A high index of suspicion, thorough clinical history, and appropriate radiological studies are essential for timely diagnosis.
- Surgical management, typically via laparotomy, remains the treatment of choice for fish bone-induced bowel perforations.

