Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 7, 2026

Point-of-care CRISPR-based Diagnostics with Premixed and Freeze-dried Reagents
10:16

Point-of-care CRISPR-based Diagnostics with Premixed and Freeze-dried Reagents

Published on: August 16, 2024

Point-of-care nucleic acid detection using nanotechnology.

Mark R Hartman1, Roanna C H Ruiz, Shogo Hamada

  • 1Department of Biological and Environmental Engineering, Cornell University, Ithaca, New York, USA. dan.luo@cornell.edu.

Nanoscale
|September 24, 2013
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Discriminating vascular parkinsonism from early-stage postural instability gait difficulty subtype dominant Parkinson's disease: a dual-task gait analysis using wearable sensors.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same author

Sex-dependent alterations of salivary microbiome in Parkinson's disease: associations with motor and non-motor clinical phenotypes.

Frontiers in molecular biosciences·2025
Same author

Alterations in gut microbiota and plasma metabolites: a multi-omics study of mild cognitive impairment in Parkinson's disease.

Frontiers in neuroscience·2025
Same author

Classifying the risk of cognitive impairment in Parkinson's disease using serum bile acid profiles and machine learning.

NPJ Parkinson's disease·2025
Same author

Corneal nerve loss measured by corneal confocal microscopy predicts pain severity in Parkinson's disease.

Neurobiology of disease·2025
Same author

Aerobic exercise modulates plasma oxidized lipid metabolites and neurotransmitters in Parkinson's disease motor subtypes.

Brain research·2025
Same journal

Curved interfaces-enhanced oxygen reduction reaction by PtCo alloys anchored MOF-derived carbon.

Nanoscale·2026
Same journal

Broadly neutralizing antibodies against HIV-1 pseudoviruses elicited by envelope trimer DNA with chimeric design delivered <i>via</i> silica-calcium phosphate nanoparticles.

Nanoscale·2026
Same journal

The transition of MXene research: the map and the gap.

Nanoscale·2026
Same journal

Critical interplay of defect engineering and plasmonics in hybrid nanostructures for ultrasensitive photo-enhanced Raman spectroscopy.

Nanoscale·2026
Same journal

Crystallization regulation and electrochemical optimization of free-standing carbon nanofiber-confined vanadium oxide nanodots for advanced flexible zinc ion batteries.

Nanoscale·2026
Same journal

Polariton manipulation <i>via</i> boundary engineering.

Nanoscale·2026
See all related articles

Nanotechnology advances portable nucleic acid detection for point-of-care (POC) diagnostics. Innovations in sample prep, amplification, and readout enable accessible DNA/RNA testing globally, especially in developing nations.

Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Molecular Diagnostics

Background:

  • Point-of-care (POC) nucleic acid detection is crucial for timely diagnostics.
  • Traditional methods often require centralized labs, limiting accessibility.
  • Nanotechnology offers potential solutions for portable and rapid detection.

Purpose of the Study:

  • To review recent nanotechnology innovations in POC nucleic acid detection.
  • To highlight advancements in sample preparation, target amplification, and detection methods.
  • To assess the impact of these innovations on decentralized and accessible testing.

Main Methods:

  • Review of recent scientific literature on nanotechnology applications in nucleic acid detection.
  • Focus on innovations in sample preparation techniques.

More Related Videos

Visual Detection of Multiple Nucleic Acids in a Capillary Array
08:56

Visual Detection of Multiple Nucleic Acids in a Capillary Array

Published on: November 15, 2017

High-throughput Detection of Respiratory Pathogens in Animal Specimens by Nanoscale PCR
11:00

High-throughput Detection of Respiratory Pathogens in Animal Specimens by Nanoscale PCR

Published on: November 28, 2016

Related Experiment Videos

Last Updated: May 7, 2026

Point-of-care CRISPR-based Diagnostics with Premixed and Freeze-dried Reagents
10:16

Point-of-care CRISPR-based Diagnostics with Premixed and Freeze-dried Reagents

Published on: August 16, 2024

Visual Detection of Multiple Nucleic Acids in a Capillary Array
08:56

Visual Detection of Multiple Nucleic Acids in a Capillary Array

Published on: November 15, 2017

High-throughput Detection of Respiratory Pathogens in Animal Specimens by Nanoscale PCR
11:00

High-throughput Detection of Respiratory Pathogens in Animal Specimens by Nanoscale PCR

Published on: November 28, 2016

  • Analysis of advancements in nucleic acid amplification strategies.
  • Examination of novel read-out modalities for POC devices.

    • Main Results:

    • Nanotechnology has significantly improved portability and sensitivity in nucleic acid detection.
    • Innovations in sample preparation enhance efficiency and reduce processing time.
    • Novel amplification techniques enable rapid and accurate target identification.
    • Advanced read-out modalities facilitate easy and accessible data interpretation.

    Conclusions:

    • Nanotechnology is a key enabler for advanced POC nucleic acid detection.
    • These advancements are crucial for improving healthcare access, particularly in resource-limited settings.
    • Further integration of nanotechnology promises more decentralized and accessible diagnostics worldwide.