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Pancreatic tumors in children
J Grochowski1, T Malek, W Miezyński
1Polish-American Institute of Paediatrics, Faculty of Medicine, Jagiellonian University, Klinika Chirurgii Dziecięcej, Wielicka 265, PL-30-663, Kraków, Poland.
Pediatric Surgery International
|September 24, 2013
Summary
Pediatric pancreatic tumors are rare and challenging to diagnose. This study reviewed five childhood cases, highlighting surgical and oncological treatment outcomes for malignant pancreatic neoplasms.
Area of Science:
- Pediatric Oncology
- Surgical Oncology
- Gastrointestinal Pathology
Background:
- Pancreatic tumors are exceptionally rare in pediatric populations.
- Clinical presentation of pancreatic tumors in children is highly variable, leading to diagnostic challenges.
- Delayed diagnosis can result in inappropriate initial management.
Purpose of the Study:
- To analyze the clinical characteristics, treatment strategies, and outcomes of pediatric pancreatic tumors.
- To evaluate the efficacy of surgical resection and adjuvant therapies in childhood pancreatic malignancies.
- To provide insights into the management of rare pancreatic neoplasms in young patients.
Main Methods:
- Retrospective review of a 26-year institutional audit (1968-1994).
- Inclusion criteria: patients aged 5-14 years operated on for pancreatic tumors.
- Analysis of surgical interventions, histopathological diagnoses, and oncological treatments (chemotherapy, radiotherapy).
Main Results:
- Five pediatric patients (ages 5-14) were identified with pancreatic tumors.
- Four of the five tumors were malignant.
- Two patients underwent primary tumor resection; three received chemotherapy and radiotherapy post-diagnosis.
- Three out of five patients survived with a mean follow-up of 9 years.
Conclusions:
- Pediatric pancreatic tumors require a high index of suspicion due to variable presentation.
- Multidisciplinary treatment including surgery and adjuvant oncology is crucial for managing malignant cases.
- Improved outcomes are achievable with timely diagnosis and appropriate therapeutic strategies in pediatric pancreatic cancer.
