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Related Concept Videos

Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
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Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
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Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids01:21

Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids

Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2 (COX-2),...
Drug Delivery: Miscellaneous Routes01:22

Drug Delivery: Miscellaneous Routes

Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
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Related Experiment Video

Updated: May 7, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
07:43

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

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[Drug therapy for acromegaly].

Miklós Góth1

  • 1Magyar Honvédség Egészségügyi Központ II. Belgyógyászati Osztály, Endokrinológiai Szakprofil Budapest Podmaniczky u. 111. 1062.

Orvosi Hetilap
|September 24, 2013
PubMed
Summary

Acromegaly, caused by excess growth hormone, leads to serious health issues. This review summarizes medical treatments like dopamine agonists and somatostatin analogues to manage the condition effectively.

Area of Science:

  • Endocrinology
  • Oncology

Background:

  • Acromegaly results from prolonged overproduction of growth hormone (GH) and insulin-like growth factor-1 (IGF-1).
  • This condition is linked to significant comorbidities and elevated mortality rates.
  • Diagnosis is often delayed despite characteristic clinical signs and advanced diagnostic methods.

Purpose of the Study:

  • To provide a comprehensive overview of medical treatment strategies for acromegaly.
  • To highlight the importance of multidisciplinary team management in treating acromegaly.
  • To discuss therapies aimed at controlling tumor growth, normalizing hormone levels, and reducing mortality.

Main Methods:

  • Review of current medical management options for acromegaly.
  • Discussion of pharmacological agents including dopamine agonists, somatostatin analogues, and GH receptor antagonists.

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Published on: February 27, 2018

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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
07:43

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A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset (Callithrix jacchus)
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A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset (Callithrix jacchus)

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  • Consideration of radiotherapy as a treatment modality.

    • Main Results:

    • Medical therapies can effectively reduce or control tumor growth and inhibit GH hypersecretion.
    • Normalization of insulin-like growth factor-1 levels is achievable with appropriate treatment.
    • Effective management of comorbidities and reduction in mortality are key outcomes of successful therapy.

    Conclusions:

    • Medical management is a cornerstone in treating acromegaly, alongside surgery and radiotherapy.
    • Multidisciplinary team approach is crucial for optimal patient outcomes.
    • Targeted therapies aim to normalize IGF-1 levels and improve overall prognosis.