Related Experiment Video
Updated: May 7, 2026
07:37
Translational Orthotopic Models of Glioblastoma Multiforme
Published on: February 17, 2023
Brain tumour mimics and chameleons
1National Hospital for Neurology and Neurosurgery, , London, UK.
Practical Neurology
|September 24, 2013
Summary
Accurate brain tumor diagnosis is vital for patient outcomes. This review highlights common neurological mimics and atypical brain tumor presentations to aid clinicians in correct diagnosis and timely treatment.
Area of Science:
- Neurology
- Neuro-oncology
Background:
- Timely brain tumor diagnosis is critical for improving patient survival rates.
- Neurological conditions can mimic brain tumors, leading to diagnostic delays.
- Atypical brain tumor presentations further complicate diagnosis and treatment initiation.
Observation:
- Common neurological disorders can present symptoms similar to brain tumors.
- Brain tumors can exhibit unusual symptoms, resembling other conditions.
- Diagnostic confusion arises from both tumor mimics and atypical tumor presentations.
Findings:
- This review details key clinical mimics of brain tumors.
- It also describes atypical brain tumor presentations ('chameleons').
- Guidance is provided for accurate diagnosis in complex cases.
Implications:
- Improved understanding of mimics and chameleons can reduce diagnostic delays.
- Accurate diagnosis optimizes patient management and treatment strategies.
- This review serves as a clinical guide for neurologists and neuro-oncologists.
Related Concept Videos
01:13Nonconscious Mimicry
Nonconscious mimicry occurs when individuals alter their mannerisms to match the behaviors and expressions of those nearby, without intention.
02:43Mouse Models of Cancer Study
Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
02:07Tumor Progression
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...