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Innovative approaches to noninvasive bone densitometry.

D J Sartoris¹, D Resnick

¹Department of Radiology, University of California, San Diego.

Critical Reviews in Diagnostic Imaging

|January 1, 1990

Summary

New noninvasive bone densitometry techniques offer improved skeletal assessment. Advanced methods like 3D CT and dual-energy radiography show promise for precise bone density measurements and fracture risk prediction.

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Area of Science:

Radiology
Medical Imaging
Bone Densitometry

Background:

Existing bone densitometry techniques have limitations.
There is a need for improved, noninvasive methods for assessing bone density.

Purpose of the Study:

To review emerging noninvasive bone densitometry techniques.
To evaluate their potential as improvements over current methods.

Main Methods:

Review of newer noninvasive bone densitometry approaches.
Discussion of three-dimensional volumetric CT, dual-energy projection radiography, Compton scattering, neutron and proton activation analysis, scanning-slit fluorography, and magnetic resonance.

Main Results:

Three-dimensional volumetric CT is practical for proximal femur density but shares CT limitations.
Dual-energy projection radiography shows potential advantages over dual-photon absorptiometry.
Compton scattering is a viable peripheral bone density alternative.
Neutron and proton activation analysis have limited application but are optimal for total body calcium.
Scanning-slit fluorography and MRI require further investigation.

Conclusions:

Several novel techniques show promise for enhancing bone density assessment.
Incentives for bone densitometry include terrestrial cost-saving and space-based research on skeletal health in microgravity.

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