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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Neurosarcoidosis: radiologic features in five patients
H Aburano1, M Hashimoto, Y Yoshie
1Department of Radiology, Kanazawa University School of Medicine; Kanazawa, Japan - aburano@arrow.ocn.ne.jp.
The Neuroradiology Journal
|September 25, 2013
Summary
Radiological features of neurosarcoidosis are highly variable, complicating diagnosis. Specific imaging findings, like pial spread and meningeal masses with characteristic T2/FLAIR signal changes, can suggest this diagnosis.
Area of Science:
- Neurology
- Radiology
- Pathology
Background:
- Neurosarcoidosis is a rare manifestation of sarcoidosis affecting the nervous system.
- Diagnosis can be challenging due to the variable clinical and imaging presentations.
Purpose of the Study:
- To describe the radiological features of biopsy-confirmed neurosarcoidosis.
- To identify imaging patterns that may aid in the diagnosis of neurosarcoidosis.
Main Methods:
- Retrospective review of five biopsy-confirmed cases of neurosarcoidosis.
- Analysis of intracranial imaging, including T2-weighted and FLAIR sequences.
Main Results:
- Imaging appearance of neurosarcoidosis is highly variable.
- Key findings include evidence of spread along the pia mater.
- Meningeal mass formation with specific T2/FLAIR signal characteristics (central low, peripheral high intensity) was observed.
Conclusions:
- Neurosarcoidosis diagnosis is difficult based solely on intracranial imaging.
- Specific imaging findings, such as pial spread and characteristic meningeal mass signal, can support the diagnosis.
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