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Rupture of a left internal jugular vein. A rare case.
F Ambesi Impiombato1, D Gambacorta, M Zocchi
1Neuroradiology Unit, Misericordia Hospital, Primary Care Trust 9; Grosseto, Italy - f.ambesi.i@gmail.com.
The Neuroradiology Journal
|September 25, 2013
Summary
Neurofibromatosis type 1 can cause spontaneous internal jugular vein rupture. This case highlights the importance of considering vascular complications in patients with this genetic disorder.
Area of Science:
- Vascular Surgery
- Genetics
- Oncology
Background:
- Neurofibromatosis type 1 (NF1) is a genetic disorder characterized by tumor formation.
- Vascular abnormalities are a known, though less common, manifestation of NF1.
Purpose of the Study:
- To report a rare case of internal jugular vein rupture in a patient with neurofibromatosis type 1.
- To investigate the underlying pathology contributing to the vascular event.
Main Methods:
- Clinical presentation and imaging (CT scan) were used to diagnose the vein rupture and hematoma.
- Histopathologic examination of the affected vessel wall was performed postoperatively.
Main Results:
- A 60-year-old woman with NF1 presented with acute neck swelling due to internal jugular vein rupture.
- Histopathology confirmed diffuse plexiform neurofibromatous tissue proliferation within the ruptured vein wall.
Conclusions:
- This case demonstrates a novel vascular complication of NF1.
- Plexiform neurofibromas can infiltrate and weaken blood vessel walls, leading to spontaneous rupture.
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