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Gender differences in the clinical characteristics of Saudi heart failure patients with subsequent stroke

Mohammad Alqahtani1, Ali AlKhtaami, Mohammed AlGobain

  • 1Dr. Mohammad Alqahtani, King Abdulaziz Medical City,, PO Box 22490, Riyadh 11426, Saudi Arabia, drqahtani@yahoo.com.

Annals of Saudi Medicine
|September 25, 2013
PubMed

Insights

This study found higher LDL cholesterol in Saudi heart failure (HF) patients with stroke, especially women. Men with stroke had higher blood urea nitrogen, suggesting gender-specific metabolic predictors for stroke in HF patients.

Area of Science:

  • Cardiology
  • Neurology
  • Metabolic Syndrome

Background:

  • Limited studies exist on stroke in Saudi Arabia.
  • Heart failure (HF) is a significant cardiovascular condition.
  • Understanding stroke risk factors in HF patients is crucial.

Purpose of the Study:

  • To determine clinical characteristics of Saudi HF patients with and without stroke.
  • To investigate gender differences in HF patients who experience stroke.
  • To identify metabolic predictors of stroke in Saudi HF patients.

Main Methods:

  • Retrospective study conducted at King Abdulaziz Medical City, Riyadh.
  • Analysis of 293 Saudi patient charts (2002-2008) diagnosed with HF.
  • Evaluation of demographics, HF characteristics, stroke risk factors, and metabolic profiles.

Main Results:

  • No significant differences in HF characteristics or stroke risk factors between HF patients with and without stroke.
  • HF patients with stroke showed significantly higher LDL-cholesterol levels.
  • Gender-specific findings: higher LDL/total cholesterol in female stroke patients, higher BUN in male stroke patients.

Conclusions:

  • Gender differences in metabolic presentation of Saudi HF patients with stroke require further study.
  • Atherogenic dyslipidemia and renal insufficiency may predict stroke in HF patients.
  • Close monitoring of these metabolic factors is recommended for Saudi HF patients.
Abstract

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