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Updated: May 7, 2026

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Published on: December 17, 2018
Voltammetric determination of folic Acid using liquid mercury free silver amalgam electrode
Abstract:
The electrochemical behavior of folic acid (FA) on a polished silver solid amalgam electrode (p-AgSAE), as a liquid mercury free electrode, has been studied in this paper. Differential pulse voltammetry (DPV) was found as a suitable method for voltammetric determination of folic acid. A limit of detection as 5.88 × 10-10 M (after 60 s of accumulation) was calculated for FA determination in an acetate buffer (pH 5). P-AgSAE in connection with DPV with optimized parameters was successfully applied for the determined folic acid compound in two types of vitamin preparations and two kinds of fruit juices. It was found that p-AgSAE is an appropriate tool for voltammetric determination of this vitamin in these real samples and it can replace mercury electrodes in voltammetric analysis of folic acid.
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