Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immunological features of diffuse connective tissue diseases.

G R Burgio1, A Martini

  • 1Clinica Pediatrica, Università di Pavia, Policlinico S. Matteo, Italy.

European Journal of Pediatrics
|January 1, 1990
PubMed
Summary

Diffuse connective tissue diseases (DCTD) are complex inflammatory disorders with unknown causes. Research into human leukocyte antigen (HLA) associations and antinuclear antibodies offers diagnostic and management insights.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Network in pediatric rheumatology: the example of pediatric rheumatology international trials organisation.

Georgian medical news·2008
Same author

Aberrant internal carotid artery in the middle ear: two case reports.

B-ENT·2008
Same author

Protection against cisplatin ototoxicity in a Sprague-Dawley rat animal model.

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale·2008
Same author

Macrophage migration inhibitory factor (MIF) and oligoarticular juvenile idiopathic arthritis (o-JIA): association of MIF promoter polymorphisms with response to intra-articular glucocorticoids.

Clinical and experimental rheumatology·2007
Same author

A longitudinal analysis of physical functional disability over the course of juvenile idiopathic arthritis.

Annals of the rheumatic diseases·2007
Same author

Measuring the psychosocial consequences of hearing loss in a working adult population: focus on validity and reliability of the Italian translation of the hearing handicap inventory.

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale·2007

Area of Science:

  • Immunology
  • Rheumatology
  • Genetics

Background:

  • Diffuse connective tissue diseases (DCTD) are a diverse group of systemic inflammatory disorders.
  • Current classification relies on clinical presentation, with complex and often unknown aetiopathogenesis.
  • A combination of environmental factors and immunogenetic predisposition is implicated.

Purpose of the Study:

  • To explore the diagnostic and clinical management implications of recent research in DCTD.
  • To highlight the role of human leukocyte antigen (HLA) associations in understanding DCTD.
  • To discuss the utility of antinuclear antibodies in DCTD diagnosis and management.

Main Methods:

  • Review of recent studies on human leukocyte antigen (HLA)-disease associations.

Related Experiment Videos

  • Analysis of research concerning antinuclear antibodies in DCTD.
  • Synthesis of clinical data for diagnosis and management strategies.

    • Main Results:

    • Human leukocyte antigen (HLA) studies have provided valuable associations for specific DCTD.
    • Antinuclear antibodies serve as important diagnostic markers for various DCTD.
    • These immunological findings offer improved diagnostic accuracy and guide clinical management.

    Conclusions:

    • Advances in HLA and antinuclear antibody research have significantly improved DCTD diagnosis.
    • Understanding immunogenetic factors is crucial for managing these complex diseases.
    • Further research into aetiopathogenesis will refine treatment strategies for DCTD.