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Prevalence of refractive errors in Möbius sequence.
Arquivos Brasileiros De Oftalmologia
|September 25, 2013
Summary
Refractive errors are common in Möbius sequence, with 42.4% of patients exhibiting them. Astigmatism was found in 40% of eyes, highlighting the need for ophthalmological assessment in these patients.
Area of Science:
- Ophthalmology
- Genetics
- Neurology
Background:
- Möbius sequence is a rare congenital disorder.
- Ocular manifestations are frequently reported in Möbius sequence.
- Comprehensive assessment is crucial for understanding the full spectrum of the condition.
Purpose of the Study:
- To determine the prevalence of refractive errors in individuals with Möbius sequence.
- To characterize the types of refractive errors present.
- To inform ophthalmological screening protocols for this population.
Main Methods:
- A cohort of 44 patients diagnosed with Möbius sequence underwent ophthalmological, neurological, genetic, psychiatric, psychological, and dental assessments.
- Visual acuity, ocular motility, cycloplegic refraction, and fundus examinations were performed.
- Data analysis focused on refractive error prevalence using spherical equivalent.
Main Results:
- Refractive errors were identified in 42.4% of the studied eyes.
- Emmetropia was observed in 57.6% of eyes.
- A significant prevalence of astigmatism (≥0.75 D) was noted in 40% of eyes.
Conclusions:
- Refractive errors represent a substantial health concern in patients with Möbius sequence.
- The high prevalence of astigmatism underscores the importance of regular eye examinations.
- Early detection and management of refractive errors can improve visual outcomes in this population.

