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[Periorbital liposarcoma in pediatric patient: a case report]
Insights
This case study details a child initially diagnosed with lipoblastoma, which later recurred as a periorbital liposarcoma. Early identification and treatment are crucial for managing this rare orbital tumor.
Area of Science:
- Pediatric Oncology
- Ophthalmology
- Surgical Pathology
Background:
- Liposarcoma is a rare malignancy, often overlooked in the differential diagnosis of orbital masses.
- Periorbital tumors in infants require careful evaluation due to potential for aggressive behavior.
Observation:
- A six-month-old female presented with a right fronto-zygomatic region tumor, initially diagnosed as lipoblastoma via histopathology and immunohistochemistry.
- The tumor relapsed three times with the same lipoblastoma diagnosis.
- A subsequent recurrence, one year after the last surgery, was diagnosed as liposarcoma.
Findings:
- The initial misdiagnosis highlights the challenge in differentiating benign and malignant soft tissue tumors in pediatric periorbital region.
- The final diagnosis of liposarcoma necessitated multimodal treatment including radiotherapy and chemotherapy.
- The patient has remained disease-free following the advanced treatment regimen.
Implications:
- This case underscores the importance of considering liposarcoma in the differential diagnosis of recurrent periorbital masses in children.
- Prompt and accurate diagnosis is vital for effective management and improved patient outcomes.
- Aggressive local behavior of liposarcoma necessitates timely intervention to prevent morbidity and enhance quality of life.
Abstract:
The purpose of this study is report a child with periorbital liposarcoma describing the clinical, epidemiological and therapeutic aspects. Six-months-old female baby with increasing tumor in the right fronto-zigomatic region wich was submitted to excision and the patologic and immunohistochemistry analisys observed typical findings of lipoblastoma. After that, there were three tumors relapse with the same diagnosis. One year after the last surgery there was a recurrence of the tumor but at this time the diagnosis was lipossarcoma and the patient was referred for additional treatment wilth radiotherapy and chemotherapy no new injuries so far Due to its rarity, liposarcoma usually does not enter the differencial diagnosis in the patients with orbital masses, however because of its local aggressiveess, it's vital the early identification and treatment to provide better therapeutic results and quality of life.
