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Published on: March 22, 2017
[Treatment strategy and prognosis analysis in children with type I esophageal atresia]
Xi-si Guan1, Jia-kang Yu, Wei Zhong
1Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China. jiakangyu@hotmail.com.
Insights
The ideal operative strategy for type I esophageal atresia depends on esophageal gap distance. Radical operations offer satisfactory outcomes for esophageal atresia management, despite potential complications.
Area of Science:
- Pediatric Surgery
- Congenital Malformations
- Gastrointestinal Surgery
Context:
- Type I esophageal atresia presents unique management challenges.
- Optimal surgical timing and approach are critical for patient outcomes.
- Limited data exists on long-term results of various operative strategies.
Purpose:
- To analyze short-term and long-term postoperative outcomes in type I esophageal atresia.
- To identify the ideal operative strategy for managing type I esophageal atresia.
- To evaluate complications, nutritional status, and neurodevelopment post-treatment.
Summary:
- Retrospective review of 22 type I esophageal atresia patients (2005-2012).
- Ten patients underwent radical operations with varying short-term (e.g., anastomotic leakage, stricture) and long-term complications (e.g., esophageal stricture, respiratory infections).
- Nutritional status showed malnutrition in 6/8 patients, and neurodevelopment was significantly delayed.
Impact:
- Findings guide the selection of operative strategy based on esophageal gap distance.
- Radical operations demonstrate relatively satisfactory efficacy regarding complications and quality of life.
- Highlights the need for ongoing management of nutritional and neurodevelopmental deficits.
Objective:
To analyze the postoperative short-term and long-term outcomes in the management of type I esophageal atresia, and to explore the ideal operative strategy.
Methods:
Clinical data of 22 patients with type I esophageal atresia treated from January 2005 to September 2012 were retrospectively reviewed. Of 22 patients, 6 patients gave up the treatment. Two underwent primary repair after birth. Of 14 patients undergoing cervical esophagostomy and gastrostomy, 8 patients received esophageal replacement. Postoperative short-term and long-term complications, nutritional state and neurodevelopment were studied on above 10 children with radical operations.
Results:
Of 10 patients with radical operation, the short-term complications were hydrothorax in 1 case, anastomotic leakage in 4, dumping syndrome in 1, anastomotic stricture in 1. The long-term complications were esophageal stricture in 2 cases, and repeated respiratory infection in 3. These complications could be managed successfully. The postoperative follow-up duration ranged from 2 to 62 months. Two cases were lost during follow-up after 2 years. Weight-for-age was normal in 2 patients, mild malnutrition in 5 patients, and moderate malnutrition in 1 patients. Neurodevelopment is significantly delayed as compared to normal children.
Conclusions:
Operative strategy should be chosen according to the distance between proximal and distal esophagus in the treatment of type I esophageal atresia. The efficacy of radical operation is relative satisfactory in terms of short-term and long-term complications and the quality of life.
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