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Related Concept Videos

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...

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Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro
08:04

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Published on: March 18, 2014

Palliative embolization for osteosarcoma.

Andreas F Mavrogenis1, Giuseppe Rossi, Eugenio Rimondi

  • 1First Department of Orthopaedics, Athens University Medical School, 41 Ventouri Street, 15562, Holargos, Athens, Greece, afm@otenet.gr.

European Journal of Orthopaedic Surgery & Traumatology : Orthopedie Traumatologie
|September 25, 2013
PubMed
Summary
This summary is machine-generated.

Selective arterial embolization effectively relieved severe pain in patients with advanced osteosarcoma. This palliative treatment provided significant pain reduction, offering a valuable option for managing refractory pain in metastatic or unresectable cases.

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Area of Science:

  • Oncology
  • Interventional Radiology

Background:

  • Osteosarcoma, particularly when metastatic, recurrent, or unresectable, carries a poor prognosis.
  • Palliative treatments aim to alleviate pain and reduce tumor size with minimal complications.

Purpose of the Study:

  • To evaluate the efficacy of palliative selective arterial embolization using N-2-butyl cyanoacrylate in patients with advanced osteosarcoma.
  • To assess pain relief, tumor response, and complications associated with this interventional radiology procedure.

Main Methods:

  • Nineteen patients with pelvic and lower lumbar spine osteosarcoma received palliative selective embolization after chemotherapy.
  • Pre-embolization angiography assessed tumor vascularity; post-embolization angiography confirmed vessel occlusion.
  • Outcomes including pain, tumor necrosis/size, and complications were monitored over an 18-month mean follow-up.

Main Results:

  • All patients achieved pain relief within 3 days post-embolization, with no recurrence of pre-embolization intensity.
  • Angiography revealed tumor hypervascularity and neovascularization in all cases.
  • Variable tumor necrosis was observed, with minimal tumor size reduction. Localized pain resolved within 1-5 days; some patients experienced transient sciatic nerve paresthesias.

Conclusions:

  • Selective arterial embolization is an effective palliative treatment for pain management in advanced osteosarcoma.
  • The procedure offers significant pain relief for patients with metastatic, recurrent, or unresectable osteosarcoma.
  • N-2-butyl cyanoacrylate embolization provides a valuable interventional option for palliative care in osteosarcoma.