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Updated: May 7, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
Published on: January 27, 2010
[Postoperative pain managements in children]
1Department of Anesthesia and Clitical Care, National Center for Child Health and Development, Tokyo 157-8535.
Insights
Pediatric pain management has advanced with new tools, but challenges remain due to limited research and opioid fears. A multimodal approach combining various analgesics is key for effective pediatric postoperative pain relief.
Area of Science:
- Pediatric Anesthesiology
- Pain Medicine
- Pharmacology
Context:
- Pediatric pain management lags behind adult analgesia due to knowledge gaps, insufficient research, and opioid concerns.
- Myths persist regarding neonates' and infants' pain perception due to immature nervous systems.
- Recognizing untreated pain as a cause of morbidity and mortality post-surgery has driven progress.
Purpose:
- To review advancements in pediatric pain assessment and management.
- To highlight current effective analgesic modalities for postoperative pediatric pain.
- To emphasize the importance of a multimodal approach in perioperative pediatric pain care.
Summary:
- Development of pediatric-specific pain assessment tools has improved care.
- Systemic opioids, NSAIDs, and regional analgesics are current treatment options.
- Multimodal strategies combining these agents offer optimal postoperative pain control.
Impact:
- Improved recognition of pain's significance in pediatric surgical patients.
- Refined techniques for accurate pain assessment across pediatric age groups.
- Enhanced postoperative pain management through integrated analgesic strategies.
Abstract:
The practice of pediatric pain management has made a great progress in the last decade with the development and validation of pain assessment tools specific to pediatric patients. Adequate pediatric pain management has not been advanced as that of adult analgesia due to a lack of clinical knowledge, insufficient pediatric research and the fear of opioid side effects and addiction. Even pediatric anesthesiologists have believed the myths that neonates and infants do not feel severe pain compared to adults because of immatured development of nervous system. The recognition that untreated pain is a significant cause of morbidity and even mortality after surgical trauma advanced in pediatric pain management. Accurate assessment of pain in different age groups and the effective treatment of postoperative pain are constantly being refined. Systemic opioids in patient-controlled analgesia, nonsteroidal antiinflammatory agents and regional analgesics alone or combined with additives are currently used to provide effective postoperative analgesia. These modalities are best utilized when combined in a multimodal approach to treat acute pain in perioperative pediatric patients.
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