Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Design of a triplex fluorescence aptasensor for a culture-free diagnosis of peritoneal dialysis-related peritonitis.

Scientific reports·2026
Same author

Co-enrichment of proteins in extracellular vesicles.

Nature communications·2026
Same author

Development of a quality control test for diphtheria vaccine based on an electrochemical aptamer-based biosensor.

Scientific reports·2026
Same author

Corrections to: An aptamer-based fluorometric microcystin-LR assay using DNA strand-based competitive displacement.

Mikrochimica acta·2026
Same author

A Wearable Microneedle-Integrated Multiplexed Photonic Aptasensor for the Detection of Illicit Drugs in Interstitial Fluid.

Analytical chemistry·2026
Same author

Engineering Aptameric Responsive Photonic Biosensor Based on Cholesteric Liquid Crystal Network for the Detection of Anatoxin.

Analytical chemistry·2025

Related Experiment Video

Updated: May 7, 2026

Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Antisense Protein (ASP) RNA Transcripts in Patients by Strand-Specific RT-PCR
08:01

Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Antisense Protein (ASP) RNA Transcripts in Patients by Strand-Specific RT-PCR

Published on: November 27, 2019

Recent progress in prostate-specific antigen and HIV proteases detection.

Ghadeer A R Y Suaifan1, Mayadah Shehadeh, Hebah Al-Ijel

  • 1Department of Pharmaceutical Sciences, Faculty of Pharmacy, The University of Jordan, Amman 11942, Jordan.

Expert Review of Molecular Diagnostics
|September 26, 2013
PubMed
Summary
This summary is machine-generated.

Developing advanced biosensing platforms for protease detection improves disease diagnosis. These sensitive and specific methods enable early detection of diseases like prostate cancer and AIDS at the point-of-care.

More Related Videos

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
13:19

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Published on: November 2, 2013

Use of Recombinant Fusion Proteins in a Fluorescent Protease Assay Platform and Their In-gel Renaturation
19:23

Use of Recombinant Fusion Proteins in a Fluorescent Protease Assay Platform and Their In-gel Renaturation

Published on: January 16, 2019

Related Experiment Videos

Last Updated: May 7, 2026

Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Antisense Protein (ASP) RNA Transcripts in Patients by Strand-Specific RT-PCR
08:01

Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Antisense Protein (ASP) RNA Transcripts in Patients by Strand-Specific RT-PCR

Published on: November 27, 2019

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
13:19

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Published on: November 2, 2013

Use of Recombinant Fusion Proteins in a Fluorescent Protease Assay Platform and Their In-gel Renaturation
19:23

Use of Recombinant Fusion Proteins in a Fluorescent Protease Assay Platform and Their In-gel Renaturation

Published on: January 16, 2019

Area of Science:

  • Biochemistry
  • Biotechnology
  • Medical Diagnostics

Background:

  • Proteases play crucial roles in biological processes and disease development.
  • Current protease detection methods face limitations in safety, sensitivity, specificity, and on-site analysis.
  • Biosensing platforms offer a promising avenue for practical protease detection applications.

Purpose of the Study:

  • To address the challenges in early disease detection, particularly for prostate cancer and AIDS.
  • To advance the development of portable detection systems for point-of-care testing.
  • To enhance the sensitivity and specificity of prognostic biomarker detection.

Main Methods:

  • Implementation of various detection methods onto biosensing platforms.
  • Development of portable detection systems for point-of-care applications.
  • Focus on detecting key prognostic biomarkers such as prostate-specific antigen and HIV load.

Main Results:

  • Biosensing platforms facilitate practical applications for protease detection.
  • Portable detection systems are being advanced for point-of-care testing.
  • Highly sensitive and specific detection of biomarkers like PSA and HIV load is a key focus.

Conclusions:

  • Advanced biosensing technologies are crucial for early disease diagnosis.
  • Point-of-care testing systems improve accessibility and timeliness of diagnostics.
  • Effective protease detection methods aid in timely treatment decisions for diseases like cancer and AIDS.