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Updated: May 7, 2026

09:14
Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
Spontaneous subperiosteal hematoma precipitated by anxiety attack
Irene M Swanenberg1, Allison E Rizzuti, Roman Shinder
1Department of Ophthalmology, SUNY Downstate Medical Center , Brooklyn, New York , USA.
Orbit (Amsterdam, Netherlands)
|September 26, 2013
Summary
A rare case of spontaneous non-traumatic subperiosteal orbital hematoma occurred in a woman after an anxiety attack. Prompt corticosteroid treatment led to rapid symptom resolution and full recovery.
Area of Science:
- Ophthalmology
- Neurology
Background:
- Subperiosteal orbital hematoma (SOH) is a rare orbital condition.
- Non-traumatic SOH (NTSOH) is exceedingly rare, often linked to bleeding disorders or sudden venous pressure increases.
Observation:
- A 60-year-old woman experienced diplopia and periorbital edema following an anxiety attack.
- Clinical examination revealed left inferotemporal globe dystopia and limited supraduction.
- Orbital MRI confirmed a superior subperiosteal orbital hematoma.
Findings:
- The patient's symptoms resolved rapidly with oral corticosteroids.
- Complete resolution of orbital signs was observed at 3-month follow-up.
- This case highlights spontaneous NTSOH triggered by an anxiety attack, a novel cause.
Implications:
- Anxiety-induced venous pressure spikes can precipitate spontaneous NTSOH.
- Early corticosteroid administration is effective for NTSOH management.
- This case expands the understanding of rare orbital hematoma etiologies.
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