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Technique of Porcine Liver Procurement and Orthotopic Transplantation using an Active Porto-Caval Shunt
Published on: May 7, 2015
A novel liver parenchyma transection technique using locking straight rigid ties. An experimental study in pigs
Dionisios Vrochides1, Dimitrios Kardassis, Achilleas Ntinas
1Hepato-Pancreato-Biliary & Transplant Division, Department of Surgery, McGill University , Montreal, QC , Canada.
Summary
A new locking straight rigid tie (LoStRiT) device significantly speeds up liver resection and reduces blood loss compared to traditional methods. This innovative technique shows promise for more efficient and cost-effective hepatic parenchymal transection.
Area of Science:
- Surgical Innovation
- Hepatic Surgery
- Minimally Invasive Techniques
Background:
- Liver resection technology is advancing, yet no single transection tool is universally superior.
- Developing effective, rapid, and economical hepatic parenchymal transection methods remains a key objective.
Purpose of the Study:
- To develop and evaluate a novel device, the locking straight rigid tie (LoStRiT), for hepatic parenchymal transection.
- To assess the efficacy, speed, and safety of the LoStRiT technique in a porcine liver resection model.
Main Methods:
- A new liver parenchyma compression device, the locking straight rigid tie (LoStRiT), was developed.
- Twelve pigs underwent hepatectomy: six in the control group (Kelly-clysis) and six in the study group (LoStRiT).
- Transection speed, blood loss, and biloma formation were measured and compared between groups.
Main Results:
- The LoStRiT group demonstrated a significantly faster mean parenchymal transection speed (2.39 cm²/min) compared to the control group (1.27 cm²/min) (p = .003).
- Mean blood loss was significantly lower in the LoStRiT group (3.9 ml/kg) versus the control group (9.8 ml/kg) (p = .040).
- No instances of biloma formation were observed in either group.
Conclusions:
- LoStRiT hepatectomy is an effective, rapid, and reproducible technique in a porcine liver resection model.
- The novel LoStRiT device offers potential for cost-efficient liver surgery.
- Future development includes constructing the LoStRiT device from absorbable materials.

