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Experimental Demyelination and Remyelination of Murine Spinal Cord by Focal Injection of Lysolecithin
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Experimental Demyelination and Remyelination of Murine Spinal Cord by Focal Injection of Lysolecithin

Published on: March 26, 2015

[Development of central pontin myelinolysis in a patient with light hyponatraemia]

Kenn Dornonville de la Cour1

  • 1Odense Universitetshospital, Svendborg Sygehus. kenn_nielsen@yahoo.dk

Ugeskrift for Laeger
|September 26, 2013
PubMed

Central pontin myelinolysis has since the 1970s been correlated with hyponatraemia. A 56-year-old woman was admitted to hospital after a few days of diminished capacity and acute disorientation and respiratory distress. Initially, her alcohol overconsumption was not recognised. She presented with only a light hyponatraemia and sepsis. Following fluid resuscitation she developed hypernatraemia and was later diagnosed with osmotic demyelination syndrome. Despite several weeks of therapy the outcome was fatal.

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