Related Experiment Video
Updated: May 7, 2026
From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia
Published on: October 19, 2014
Extramedullary chronic lymphocytic leukemia: systematic analysis of cases reported between 1975 and 2012
Megan Ratterman1, Kimberly Kruczek1, Suela Sulo2
1Department of Medicine, Advocate Lutheran General Hospital, Park Ridge, IL, United States.
Abstract:
The prognostic significance of extra-medullary chronic lymphocytic leukemia (EM-CLL) is unknown. We conducted a Medline database systematic search analyzing English language articles published between 1975 and 2012 identifying 192 cases. Patients with EM-CLL were more commonly treated than not (p < .001). Skin and central nervous system (CNS) were the most commonly reported sites of organ involvement. Survival after diagnosis of EM-CLL appeared to depend on the site of EM involvement. Prospective evaluation and further studies of EM-CLL are warranted.
