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Related Experiment Video

Updated: May 7, 2026

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Modified dextrose prolotherapy for recurrent temporomandibular joint dislocation.

H Zhou1, K Hu1, Y Ding1

  • 1Department of Oral and Maxillofacial Surgery, School of Stomatology, Fourth Military Medical University (FMMU), Xi'an, China.

The British Journal of Oral & Maxillofacial Surgery
|September 26, 2013
PubMed
Summary

A modified dextrose prolotherapy effectively treats recurrent temporomandibular joint (TMJ) dislocation. This simple, safe injection technique showed a 91% success rate in patients, reducing dislocation and clicking episodes.

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Area of Science:

  • Orthopedics
  • Pain Management
  • Regenerative Medicine

Background:

  • Recurrent temporomandibular joint (TMJ) dislocation presents a challenge for patients seeking conservative treatments.
  • Patients expect simple procedures with predictable outcomes for TMJ disorders.

Purpose of the Study:

  • To evaluate the efficacy of a modified prolotherapy technique for treating non-neurogenic recurrent TMJ dislocation.
  • To assess the safety and cost-effectiveness of this novel TMJ treatment.

Main Methods:

  • A modified prolotherapy technique involving lignocaine and 50% dextrose injections into posterior periarticular tissues was used.
  • The study included 45 patients (age 17-59) with recurrent TMJ dislocation.
  • Treatment outcomes were assessed over a follow-up period exceeding one year.
Keywords:
DextroseDislocationProlotherapyTemporomandibular joint

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Main Results:

  • A high overall success rate of 91% (41/45 patients) was observed, defined as no further dislocation or subluxation for over 6 months.
  • Significant improvements in the frequency of dislocation and TMJ clicking were reported post-injection.
  • Most patients (63%) required only a single injection, with others needing two or three treatments.

Conclusions:

  • Modified dextrose prolotherapy is a simple, safe, and cost-effective treatment for recurrent TMJ dislocation.
  • This technique offers appreciable benefits, including reduced dislocation episodes and clicking.
  • The high success rate supports its consideration as a viable conservative intervention for TMJ instability.