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Updated: May 5, 2026

Isolation and Culture of Adult Epithelial Stem Cells from Human Skin
Published on: March 31, 2011
Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche
Guiomar Solanas1, Salvador Aznar Benitah
11] Centre for Genomic Regulation (CRG), Dr. Aiguader 88, 08003 Barcelona, Spain. [2].
Abstract:
In the past years, our view of the molecular and cellular mechanisms that ensure the self-renewal of the skin has dramatically changed. Several populations of stem cells have been identified that differ in their spatio-temporal contribution to their compartment in steady-state and damaged conditions, suggesting that epidermal stem cell heterogeneity is far greater than previously anticipated. There is also increasing evidence that these different stem cells require a tightly controlled spatial and temporal communication between other skin residents to carry out their function.
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