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Factors influencing thyroid volume in Chinese children

Y Zou1, G Ding, X Lou

  • 1Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.

European Journal of Clinical Nutrition
|September 26, 2013
PubMed

Insights

Thyroid volume in Zhejiang children is influenced by age, gender, and body surface area, not iodine levels. Optimal iodine status was observed, but it did not significantly impact thyroid size in this age group.

Area of Science:

  • Pediatric Endocrinology
  • Environmental Health
  • Public Health Nutrition

Background:

  • Thyroid volume (Tvol) is a key indicator of thyroid health in children.
  • Assessing Tvol and its determinants is crucial for monitoring child health in specific regions.
  • Iodine status is vital for thyroid function, but its direct impact on Tvol requires regional investigation.

Purpose of the Study:

  • To compare children's thyroid volume (Tvol) by age and gender in Zhejiang province.
  • To explore the factors influencing Tvol in Zhejiang province children.
  • To assess the relationship between urinary iodine concentration (UIC) and Tvol.

Main Methods:

  • Cross-sectional survey of a representative sample of Zhejiang province children aged 6-12 years.
  • Determination of urinary iodine concentration (UIC) from urine samples.
  • Thyroid ultrasonography for the measurement of Tvol and body surface area (BSA).

Main Results:

  • Median UIC was 170.0 μg/l, indicating optimal iodine status.
  • Median Tvol was 3.1 ml.
  • Tvol showed significant associations with age, gender, and BSA, but not with UIC.

Conclusions:

  • Children in Zhejiang province aged 6-12 years exhibit optimal iodine status.
  • Urinary iodine nutritional status had minimal effect on Tvol in this population.
  • Age, gender, and body surface area are significant influencing factors for Tvol in Zhejiang children.
Abstract

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