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Related Experiment Video

Updated: May 7, 2026

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

Platelet function in euthyroid patients undergoing thyroidectomy in women.

A Alcelik¹, G Aktas, M Eroglu

¹Department of Internal Medicine, Izzet Baysal Medical Faculty, Bolu, Turkey. aytekinalcelik@yahoo.com

European Review for Medical and Pharmacological Sciences

|September 26, 2013

Summary

Thyroid gland tissue does not directly impact platelet function in euthyroid females. Platelet abnormalities in thyroid disease are linked to hormone levels, not the gland itself.

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Area of Science:

Endocrinology
Hematology
Surgical Research

Background:

Thyroid dysfunction is linked to platelet abnormalities.
Thyroid hormone levels significantly influence hemostatic balance.
The direct effect of thyroid tissue on platelet function remains unclear.

Purpose of the Study:

To investigate platelet function in euthyroid females undergoing thyroidectomy.
To differentiate the impact of thyroid tissue versus hormones on platelet activity.

Main Methods:

Compared 52 euthyroid females undergoing thyroidectomy with 21 healthy controls.
Measured platelet count (PC), platelet mass (PM), mean platelet volume (MPV), and platelet distribution width (PDW).
Calculated PM using MPV and PLT.

Main Results:

Mean platelet volume (MPV) was similar between study and control groups (8.4 ± 1.3 vs. 7.9 ± 0.8).
Platelet distribution width (PDW) was also similar (17.8 ± 1 vs. 17.6 ± 0.8).

Conclusions:

The thyroid gland itself does not directly influence platelet activation.
Platelet abnormalities associated with thyroid disease are independent of thyroid tissue.
The relationship between thyroid disease and platelet function is primarily mediated by thyroid hormone status.