Related Experiment Video
Updated: May 7, 2026

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
First-trimester sonographic findings associated with a Dandy-Walker malformation and inferior vermian hypoplasia
Eran Bornstein1, José Luis Goncalves Rodríguez, Erika Carolina Álvarez Pavón
1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Lenox Hill Hospital, North Shore-LIJ, 130 E 77th St, New York, NY 10075 USA. eranbor@yahoo.com.
Abstract:
We report 2 cases in which first-trimester measurements of the intracranial translucency and the brain stem-to-occipital bone diameter were markedly enlarged. This finding was thought to represent an abnormal fourth ventricle-cisterna magna complex. Subsequently, the diagnoses of a Dandy-Walker malformation with partial vermian agenesis in 1 case and inferior vermian hypoplasia in the other were established and confirmed by either postmortem autopsy or postnatal magnetic resonance imaging. These cases suggest that evaluation of the fourth ventricle-cisterna magna complex, by measuring the intracranial translucency or brain stem-to-occipital bone diameter may identify some cases with structural malformations of the cerebellum as early as the first trimester.
Related Concept Videos
Teratogenicity
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Development of Blood Vessels
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...

