Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Focusing of Light in the Eye01:16

Focusing of Light in the Eye

Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Risk Factors and Predictive Model for Postoperative High Myopia in Children Undergoing Congenital Cataract Surgery With Intraocular Lens Implantation.

American journal of ophthalmology·2026
Same author

Ultrafast line-field holographic elastography with single excitation for corneal biomechanical characterization.

Biomedical optics express·2026
Same author

Different retinal microvascular response to flicker light between normal-tension glaucoma and high-tension primary open-angle glaucoma detected with optical coherence tomography angiography.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2025
Same author

Short-Term Effects of Dark Chocolate on Choroidal Parameters in Myopic Patients During Near Work.

Current eye research·2025
Same author

Ultra-fast line-field swept source scanning optical coherence elastography.

Biomedical optics express·2025
Same author

Diagnostic accuracy of optic disc microvasculature dropout for detecting glaucoma in eyes with high myopia.

The British journal of ophthalmology·2025

Related Experiment Video

Updated: May 7, 2026

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
05:14

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter

Published on: September 16, 2025

Ocular anterior segment biometry and high-order wavefront aberrations during accommodation.

Yimin Yuan1, Yilei Shao, Aizhu Tao

  • 1School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.

Investigative Ophthalmology & Visual Science
|September 26, 2013
PubMed
Summary
This summary is machine-generated.

Ocular high-order aberrations (HOAs) increase during accommodation due to changes in anterior segment biometry, particularly lens shape. Pupil constriction may help mitigate these HOAs.

Keywords:
aberrationsaccommodationanterior segmentcrystalline lensoptical coherence tomographypupil

More Related Videos

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes
08:27

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes

Published on: March 3, 2023

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
05:46

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Related Experiment Videos

Last Updated: May 7, 2026

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
05:14

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter

Published on: September 16, 2025

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes
08:27

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes

Published on: March 3, 2023

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
05:46

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Area of Science:

  • Ophthalmology
  • Optometry
  • Biomedical Optics

Background:

  • Accommodation involves dynamic changes in ocular structures to maintain focus.
  • High-order aberrations (HOAs) affect visual quality beyond refractive error.
  • Understanding accommodation-induced changes in anterior segment biometry and HOAs is crucial for visual optics research.

Purpose of the Study:

  • To investigate the relationship between ocular anterior segment biometry and high-order aberrations (HOAs) during accommodation.
  • To quantify changes in anterior segment dimensions and HOAs using combined ultralong scan depth optical coherence tomography (UL-OCT) and wavefront sensing.

Main Methods:

  • Utilized a custom-built UL-OCT and wavefront sensor system.
  • Recruited 35 healthy young subjects (21 female, 14 male).
  • Measured anterior segment biometry and HOAs in both non-accommodative and accommodative states.

Main Results:

  • Accommodation significantly decreased anterior chamber depth, pupil diameter, and lens surface radii, while increasing lens thickness.
  • Root-mean-square of HOAs (HORMS) increased significantly with accommodation (P < 0.01).
  • Negative correlation found between anterior lens surface curvature change and HORMS change (r = -0.370, P = 0.014).
  • HORMS negatively correlated with pupil diameter in both states (r = -0.532 to -0.801, P < 0.01).

Conclusions:

  • Accommodation induces significant changes in anterior segment biometry and HOAs.
  • Increased lens anterior surface convexity is a primary driver of accommodation-induced HOAs.
  • Pupil constriction during accommodation may serve to reduce HOAs.