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Related Experiment Video

Updated: May 7, 2026

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

Published on: January 22, 2016

Does Posttraumatic Stress Disorder (PTSD) Affect Post-Treatment Methamphetamine Use?

Suzette Glasner-Edwards¹, Larissa J Mooney, Alfonso Ang

¹UCLA Integrated Substance Abuse Programs.

Journal of Dual Diagnosis

|September 26, 2013

Summary

This summary is machine-generated.

Posttraumatic stress disorder (PTSD) significantly worsens treatment outcomes for methamphetamine users, increasing relapse risk and psychiatric impairment. Addressing PTSD symptoms is crucial for improving recovery in this population.

Keywords:

PTSD comorbidity methamphetamine outcome treatment

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Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

Published on: October 10, 2012

Area of Science:

Psychiatry
Addiction Medicine
Trauma Studies

Background:

Trauma is a known risk factor for substance use disorders.
The link between posttraumatic stress disorder (PTSD) and treatment outcomes in methamphetamine users is not well understood.

Purpose of the Study:

To examine the relationship between PTSD and methamphetamine use outcomes post-treatment.
To investigate PTSD's association with hospitalizations and psychiatric impairment.
To identify PTSD symptom clusters as predictors of relapse.

Main Methods:

Analysis of data from 526 adults in a large psychosocial clinical trial for methamphetamine users.
Examined treatment outcomes three years post-treatment for individuals with co-occurring PTSD.
Assessed PTSD symptom clusters as risk factors for relapse.

Main Results:

PTSD diagnosis was linked to poorer methamphetamine use outcomes over 3 years.
Individuals with PTSD had over five times the odds of recent methamphetamine use (OR=5.2).
Higher levels of other psychiatric conditions and specific PTSD symptoms (avoidance, arousal) predicted relapse.

Conclusions:

Effective treatment for methamphetamine users may require addressing co-occurring PTSD.
Targeting PTSD symptoms could improve methamphetamine use disorder treatment outcomes.
Integrated care for PTSD and substance use is recommended.