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Polyhydramnios with maternal lithium treatment.

S Krause¹, F Ebbesen, A P Lange

¹Department of Obstetrics and Gynecology, Copenhagen University Hospital, Glostrup, Denmark.

Obstetrics and Gynecology

|March 1, 1990

Summary

Severe polyhydramnios in a fetus may indicate lithium toxicity, even when maternal lithium levels are therapeutic. This toxicity can lead to serious infant health issues, highlighting the need for careful monitoring during pregnancy.

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Area of Science:

Perinatology
Toxicology
Maternal-Fetal Medicine

Background:

Lithium is used to treat bipolar disorder (manic-depressive psychosis).
Maternal lithium treatment during pregnancy can pose risks to the fetus.
Polyhydramnios, excessive amniotic fluid, can indicate fetal complications.