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Published on: June 11, 2011

Blood Transfusion-Associated HIV Infection in Children in Ibadan, Nigeria

Biobele J Brown1, Regina E Oladokun1, Babatunde O Ogunbosi1

  • 11 Department of Paediatrics, College of Medicine, University of Ibadan, and University College Hospital, Ibadan, Nigeria.

Journal of the International Association of Providers of AIDS Care
|September 27, 2013
PubMed

Insights

Blood transfusion-associated HIV infection (TAHI) is a rare but serious concern in Nigerian children. Implementing optimal blood safety practices is crucial for preventing TAHI transmission.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Epidemiology

Background:

  • Blood transfusion-associated HIV infection (TAHI) poses a public health challenge.
  • Understanding the epidemiology of TAHI in children is essential for prevention.

Purpose of the Study:

  • To describe the epidemiologic features and clinical course of TAHI in Nigerian children.
  • To compare TAHI with vertically acquired HIV infection in children.

Main Methods:

  • Retrospective study of children diagnosed with TAHI at University College Hospital, Ibadan.
  • Comparison with a pediatric HIV database of vertically infected children.

Main Results:

  • TAHI accounted for 2.3% of pediatric HIV cases (14/597) between 2004-2011.
  • Mean age at diagnosis was significantly higher for TAHI (10.2 years) vs. vertical transmission (3.9 years).
  • Blood transfusions occurred in both private (9 cases) and public (5 cases) hospitals.

Conclusions:

  • Optimal blood safety practices are recommended to prevent TAHI in Nigeria.
  • Enhanced screening and safety measures are vital for blood transfusions.
Abstract

Keywords:
AIDSchildrentransfusion-associated HIV

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