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Fixed drug eruption caused by tadalafil--case report
Milan Bjekic1, Milica Markovic, Sandra Sipetic
1venereological department, City Institute for Skin and Venereal Diseases, Belgrade, Serbia.
Anais Brasileiros De Dermatologia
|September 27, 2013
Summary
Fixed drug eruptions (FDE) are a common mucocutaneous reaction. This case highlights oral tadalafil as a potential cause, with lesions resolving after topical treatment.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Fixed drug eruptions (FDE) represent a significant category of mucocutaneous drug reactions.
- Identifying causative agents is crucial for effective patient management.
Observation:
- A case study involving a patient presenting with multiple erythema fixum lesions.
- Lesions were attributed to the use of oral tadalafil.
Findings:
- Topical corticosteroid therapy led to complete resolution of skin lesions.
- Residual hyperpigmentation was noted post-treatment.
- Gingival hyaluronic acid 0.2% gel proved effective for oral mucosal lesions.
Implications:
- Healthcare providers should inquire about phosphodiesterase type 5 inhibitor use in patients with drug eruptions.
- Awareness of tadalafil-induced FDE is important for diagnosis and treatment.
- This case broadens the understanding of drug-induced mucocutaneous reactions.
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