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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

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Case for diagnosis: Linear Darier.

Fernanda Guedes Lavorato¹, Luna Azulay-Abulafia, Vanessa Ramos

¹Rio de Janeiro(RJ), Brazil.

Anais Brasileiros De Dermatologia

|September 27, 2013

Summary

This summary is machine-generated.

Linear Darier disease, a rare skin condition, presents as papules along Blaschko's lines. This case highlights the characteristic cutaneous mosaicism and histological findings of this rare Darier's disease variant.

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Area of Science:

Dermatology
Genetics
Histopathology

Background:

Darier's disease is a rare autosomal dominant genodermatosis.
Linear Darier is an extremely rare variant presenting with cutaneous mosaicism.

Observation:

A 42-year-old woman presented with linearly distributed, reddish-brown papules.
Lesions were observed on the left mammary region, flank, hypogastrium, and left pretibial area.

Findings:

Histopathological examination revealed suprabasal acantholysis.
Dyskeratotic cells were identified, confirming the diagnosis of Linear Darier disease.

Implications:

This case contributes to the understanding of rare genodermatoses.
Recognizing linear patterns is crucial for diagnosing Darier's disease variants.
Cutaneous mosaicism provides insights into postzygotic mutations.