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Updated: May 7, 2026
Transcranial Direct Current Stimulation and Simultaneous Functional Magnetic Resonance Imaging
Published on: April 27, 2014
The effect of transcranial direct current stimulation: a role for cortical excitation/inhibition balance?
Beatrix Krause1, Javier Márquez-Ruiz, Roi Cohen Kadosh
11Department of Experimental Psychology, University of Oxford Oxford, Oxfordshire, UK.
Abstract:
Transcranial direct current stimulation (tDCS) is a promising tool for cognitive enhancement and neurorehabilitation in clinical disorders in both cognitive and clinical domains (e.g., chronic pain, tinnitus). Here we suggest the potential role of tDCS in modulating cortical excitation/inhibition (E/I) balance and thereby inducing improvements. We suggest that part of the mechanism of action of tDCS can be explained by non-invasive modulations of the E/I balance.
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