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Infantile extrapancreatic pancreatoblastoma: a report on a rare infantile abdominal mass
Hossein Esfahani1, Elham Olad, Arash Dehghan
1Departments of *Pediatric Hematology/Oncology †Pediatrics ‡Pathology §Pediatric Gastroenterology, Hamadan University of Medical Science, Hamadan, Islamic Republic of Iran.
Insights
This report details a rare case of pancreatoblastoma in a 3-month-old infant. The tumor, found outside the pancreas, was successfully resected, highlighting early detection and surgical intervention for pediatric abdominal masses.
Area of Science:
- Pediatric Oncology
- Surgical Pathology
Background:
- Pancreatoblastoma is an exceptionally rare pediatric tumor, with even rarer occurrences in infants under three months.
- Ectopic pancreatic tissue can serve as a site for tumor origin, complicating diagnosis and surgical planning.
Observation:
- A 3-month-old male presented with a large abdominal mass.
- CT imaging identified a lobulated mass anterior to the kidneys, featuring calcification and contrast enhancement.
- The mass was surgically resected from the transverse mesocolon, separate from the pancreas.
Findings:
- Pathological examination confirmed the diagnosis of pancreatoblastoma.
- The tumor's extra-pancreatic origin was a notable characteristic.
Implications:
- This case underscores the importance of considering rare diagnoses like pancreatoblastoma in infants with abdominal masses.
- Complete surgical resection is a viable primary treatment, even for extra-pancreatic pancreatoblastomas.
- The successful outcome emphasizes the need for vigilant postsurgical follow-up in pediatric oncology cases.
Abstract:
Pancreatoblastoma is an extremely rare tumor in children, especially under 3 months of age. This tumor may arise from any portion of the pancreas, but in more rare cases the ectopic pancreas is the origin. We are reporting a 3-month-old boy who was presented with an abdominal mass. Computed tomography images revealed a huge lobulated mass anterior to the kidneys, with internal calcification and enhancement after intravenous contrast media injection. He underwent a complete surgical resection of the mass that was located in the transverse mesocolon without any connection with the pancreas. Pathologic studies specified that the disease was pancreatoblastoma. His parents refused any chemotherapeutic regimen but continued postsurgical follow-ups.
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