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Radiographic findings in Waldenström's macroglobulinemia resembling fibrogenesis imperfecta ossium (FIO): a case

Narendranath Epperla1, Fergus E McKiernan, Charles V Kenney

  • 1Department of Internal Medicine, Marshfield Clinic, 1000 N Oak Ave, Marshfield, WI, 54449, USA, enaren10@gmail.com.

Skeletal Radiology
|September 28, 2013
PubMed

Insights

This case study highlights a rare association between Waldenström's macroglobulinemia and fibrogenesis imperfecta ossium. Radiographic findings may be more common than previously thought, necessitating bone biopsy for diagnosis.

Area of Science:

  • Hematology
  • Radiology
  • Pathology

Background:

  • Waldenström's macroglobulinemia is a rare lymphoproliferative disorder.
  • Fibrogenesis imperfecta ossium is a rare genetic bone disorder.

Observation:

  • A patient presented with Waldenström's macroglobulinemia and radiographic findings suggestive of fibrogenesis imperfecta ossium.

Findings:

  • The co-occurrence of these conditions was observed.
  • Radiographic features of fibrogenesis imperfecta ossium may be underrecognized in Waldenström's macroglobulinemia.

Implications:

  • This case suggests a potential link between the two conditions.
  • Bone biopsy is crucial for definitive diagnosis of fibrogenesis imperfecta ossium in such cases.

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