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Nonpharmacological management of gastroesophageal reflux in preterm infants

Luigi Corvaglia1, Silvia Martini, Arianna Aceti

  • 1Neonatology and Neonatal Intensive Care Unit, S. Orsola-Malpighi Hospital, Via Massarenti 11, 40138 Bologna, Italy ; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti 9, 40138 Bologna, Italy.

Biomed Research International
|September 28, 2013
PubMed

Insights

Gastroesophageal reflux (GOR) in preterm infants is common. Conservative, non-pharmacological strategies like positioning and feeding changes are recommended before considering medication for GOR management.

Area of Science:

  • Neonatology
  • Pediatric Gastroenterology

Background:

  • Gastroesophageal reflux (GOR) is highly prevalent in preterm infants due to physiological factors.
  • Current management of GOR in neonates is controversial, with a trend towards potentially harmful pharmacological overtreatment.

Purpose of the Study:

  • To review the evidence on conservative, non-pharmacological management of GOR in preterm infants.
  • To evaluate the benefits and adverse effects of non-pharmacological interventions for GOR.

Main Methods:

  • Systematic review of current literature on non-pharmacological GOR management in preterm infants.
  • Analysis of conservative strategies including body positioning, milk thickening, and feeding modifications.

Main Results:

  • Conservative strategies are advisable as a first-line approach for GOR in preterm infants.
  • Non-pharmacological measures can effectively manage GOR, potentially reducing the need for medication.

Conclusions:

  • Non-pharmacological management is a valuable tool for neonatologists treating GOR in preterm infants.
  • Antireflux medications should be reserved for selected symptomatic cases, emphasizing conservative care first.

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