Related Experiment Video
Updated: May 7, 2026

Induction and Phenotyping of Acute Right Heart Failure in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension
Published on: March 17, 2022
Treatment of acute heart failure in the emergency department
Peter S Pang1, Phillip Levy, Sanjiv J Shah
1Department of Emergency Medicine, Northwestern University Feinberg School of Medicine, 211 E Ontario St, Suite 300, Chicago, IL 60611, USA.
Insights
Acute heart failure (AHF) affects millions globally, with high mortality and rising prevalence. Current initial treatments are outdated, necessitating advancements in AHF management strategies to improve patient outcomes.
Area of Science:
- Cardiology
- Internal Medicine
- Critical Care Medicine
Background:
- Acute heart failure (AHF) is a major cause of hospitalization worldwide.
- Despite advances in cardiovascular care, AHF morbidity and mortality remain high.
- The aging population is projected to increase the incidence and prevalence of heart failure (HF).
Purpose of the Study:
- To review recent advances in the initial management of acute heart failure.
- To highlight the unmet need for improved outcomes in AHF patients.
Main Methods:
- Review of multiple studies on initial AHF management.
- Analysis of current treatment and care strategies for early AHF.
Main Results:
- Current initial AHF treatment has not significantly evolved over the past 40 years.
- New insights into AHF management have emerged from recent studies.
Conclusions:
- There is a critical need to update and improve initial treatment protocols for acute heart failure.
- Further research and implementation of advanced strategies are required to reduce AHF morbidity and mortality.
Abstract:
Millions of patients are hospitalized for acute heart failure (AHF) every year throughout the world. Despite tremendous advances in cardiovascular care, morbidity and mortality for AHF remain high, consuming billions of health care dollars. With the aging of the population, the incidence and prevalence of HF is projected to increase. Yet, initial treatment of AHF today is similar to 40 years ago. Multiple studies have yielded new insights regarding initial management, with regards to both treatment and strategies of care. These advances will be reviewed in the context of initial or early AHF management. There remains, however, an unmet need to improve outcomes for AHF patients.
Related Concept Videos
Heart Failure V: Medical Management
Heart Failure VI: Adjunct Therapies
Acute Coronary Syndrome IV: Interprofessional Care
Acute Coronary Syndrome V: Nursing Management
Heart Failure IV: Classification and Diagnostic Evaluation
Heart Failure VII: Nursing Interventions
