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Updated: May 7, 2026

Efficient Purification of Elastin-Like Polypeptides (ELPs) from E. coli Using an Organic Solvent-based Extraction and Precipitation Method
Published on: January 9, 2026
Stimuli responsive elastin-like polypeptides and applications in medicine and biotechnology
Yuezai Shang1, Yufang Yan, Xin Hou
1a Tianjin Key Laboratory of Composite and Functional Materials , , Tianjin , 300072 , P.R. China .
Abstract:
Elastin-like polypeptides (ELPs) are artificial biopolymers composed of the pentapeptide repeat Val-Pro-Gly-Xaa-Gly. They are a class of stimuli responsive biopolymers exhibiting an inverse temperature transition, which are particularly attractive in biological applications. In this paper, the methods of synthesizing ELPs and the applications in medicine and biotechnology such as purification of fusion proteins, drug delivery, and tissue engineering are reviewed. In addition, further perspective will be presented.

