Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Studying the Cytoskeleton

Studying the Cytoskeleton

The cytoskeletal architecture can be studied using different microscopic and biochemical techniques. Electron microscopy was instrumental in discovering the cytoskeletal architecture around the 1960s, which allowed obtaining structural information at a high-resolution level. However, the sample preparation procedure often limits this ability in biological samples. Several protocols have been developed over the years to optimize sample preparation. In one of the protocols known as rotary...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

AI-Enhanced Adaptive Virtual Screening Platform Enabling Exploration of 69 Billion Molecules Discovers Structurally Validated FSP1 Inhibitors.

bioRxiv : the preprint server for biology·2026

Same author

Corrections to "Discovery of the Cytocapsular Membrane as Hallmark of Malignant Tumors".

Biochemistry·2026

Same author

Scalable deep learning reconstruction for accelerated multidimensional nuclear magnetic resonance spectroscopy of proteins.

Science advances·2025

Same author

Biophysical and Structural Features of αβT-Cell Receptor Mechanosensing: A Paradigmatic Shift in Understanding T-Cell Activation.

Immunological reviews·2025

Same author

Discovery of the Cytocapsular Membrane as Hallmark of Malignant Tumors.

Biochemistry·2024

Same author

Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5.

Cell reports·2024

Same journal

Metabolic disruptions through a three-dimensional genomic lens.

Current opinion in structural biology·2026

Same journal

Collective variable design for biomolecular conformational dynamics.

Current opinion in structural biology·2026

Same journal

Polymer scaling in protein crowding: From dilute coils to semidilute meshes.

Current opinion in structural biology·2026

Same journal

Tuning the physicochemical properties of rationally designed protein-based biomolecular condensates.

Current opinion in structural biology·2026

Same journal

Editorial overview: Folding, binding and protein design.

Current opinion in structural biology·2026

Same journal

Macromolecular crowding reshapes the conformational landscapes of intrinsically disordered proteins: mechanisms, cellular contexts, and functional consequences.

Current opinion in structural biology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 7, 2026

Using Expansion Microscopy to Physically Enlarge Whole-Mount Drosophila Embryos for Super-Resolution Imaging

Using Expansion Microscopy to Physically Enlarge Whole-Mount Drosophila Embryos for Super-Resolution Imaging

Published on: April 28, 2023

Exploring new limits in complex biological structures

Gerhard Wagner¹, Wah Chiu

¹Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.

Current Opinion in Structural Biology

|October 1, 2013

Summary

No abstract available in PubMed .

More Related Videos

Visualizing Single Molecular Complexes In Vivo Using Advanced Fluorescence Microscopy

Visualizing Single Molecular Complexes In Vivo Using Advanced Fluorescence Microscopy

Published on: September 8, 2009

Nanoscopic Imaging of Human Tissue Sections via Physical and Isotropic Expansion

Nanoscopic Imaging of Human Tissue Sections via Physical and Isotropic Expansion

Published on: September 25, 2019

Related Experiment Videos

Last Updated: May 7, 2026

Using Expansion Microscopy to Physically Enlarge Whole-Mount Drosophila Embryos for Super-Resolution Imaging

Using Expansion Microscopy to Physically Enlarge Whole-Mount Drosophila Embryos for Super-Resolution Imaging

Published on: April 28, 2023

Visualizing Single Molecular Complexes In Vivo Using Advanced Fluorescence Microscopy

Visualizing Single Molecular Complexes In Vivo Using Advanced Fluorescence Microscopy

Published on: September 8, 2009

Nanoscopic Imaging of Human Tissue Sections via Physical and Isotropic Expansion

Nanoscopic Imaging of Human Tissue Sections via Physical and Isotropic Expansion

Published on: September 25, 2019