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CD301b⁺ dermal dendritic cells drive T helper 2 cell-mediated immunity

Yosuke Kumamoto1, Melissa Linehan, Jason S Weinstein

  • 1Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

Immunity
|October 1, 2013
PubMed
Summary

Dendritic cells (DCs) expressing CD301b are crucial for initiating T helper 2 (Th2) cell responses. These specific DCs transport antigens and are essential for effective Th2 cell development and interleukin-4 production.

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