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Mitochondrial dysfunction and oxidative damage cooperatively fuel axonal degeneration in X-linked

Stéphane Fourcade1, Jone López-Erauskin1, Montserrat Ruiz1

  • 1Neurometabolic Diseases Laboratory, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Hospitalet de Llobregat, 08908 Barcelona, Catalonia, Spain; Institute of Neuropathology, Pathologic Anatomy Service, Bellvitge Biomedical Research Institute, IDIBELL - Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, 08908 Barcelona, Spain; Center for Biomedical Research on Rare Diseases (CIBERER), U759, ISCIII, Spain.

Biochimie
|October 1, 2013
PubMed

Keywords:
Cyclophilin DMitochondria dysfunctionOxidative damageProteasomeVery long-chain fatty acidsX-linked adrenoleukodystrophy

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