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Related Concept Videos

What is Genetic Engineering?00:49

What is Genetic Engineering?

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Transgenic Organisms00:53

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Transgenic Organisms00:53

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In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
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Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
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Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...

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Updated: May 7, 2026

Generation of Genetically Modified Mice through the Microinjection of Oocytes
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Natural genotypes via genetic engineering

Kevin D Wells1

  • 1Division of Animal Sciences, College of Agriculture and Natural Resources, and National Swine Resource and Research Center, University of Missouri, Columbia, MO 65211.

Proceedings of the National Academy of Sciences of the United States of America
|October 1, 2013
PubMed
Summary

No abstract available in PubMed .

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