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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Preventive Healthcare Services01:30

Preventive Healthcare Services

Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...

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Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
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Identifying risk factors using a skin cancer screening program.

Jeremy R Etzkorn1, Rajiv P Parikh, Suroosh S Marzban

  • 1University of South Florida, College of Medicine, Department of Dermatology and Cutaneous Surgery, Tampa, FL 33612, USA. mlien@health.usf.edu.

Cancer Control : Journal of the Moffitt Cancer Center
|October 1, 2013
PubMed
Summary

Skin cancer screening identifies nonmelanoma skin cancer (NMC) risk factors in adults. Younger individuals (<50) with changing moles may benefit most from screening for suspicious pigmented lesions.

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Last Updated: May 7, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
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Published on: September 7, 2013

Quantitative Visualization and Detection of Skin Cancer Using Dynamic Thermal Imaging
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Cell Population Analyses During Skin Carcinogenesis

Published on: August 21, 2013

Area of Science:

  • Dermatology
  • Public Health
  • Epidemiology

Background:

  • Rising incidence of melanoma and nonmelanoma skin cancer (NMC).
  • Skin cancer screening programs are proposed for early lesion detection.
  • Effectiveness and target populations for screening remain under investigation.

Purpose of the Study:

  • To examine the relationship between known risk factors and presumptive diagnoses in individuals attending a free skin cancer screening.
  • To identify demographic and exposure factors associated with nonmelanoma cancer and suspicious pigmented lesions.

Main Methods:

  • Descriptive cross-sectional study utilizing data from a skin cancer screening program (2007-2010).
  • Standardized medical history forms collected participant data prior to skin examination.
  • Diagnoses were categorized as nonmelanoma cancer (NMC) or suspicious pigmented lesion.

Main Results:

  • NMC diagnosis correlated with male sex, age ≥ 50, prior skin cancer history, lower skin phototype, and increased sun exposure.
  • Sunscreen use was not independently associated with NMC diagnosis after controlling for skin phototype.
  • Suspicious pigmented lesions were linked to a history of changing moles and were more common in individuals < 50 years old.

Conclusions:

  • Established risk factors for NMC were associated with presumptive NMC diagnoses.
  • Individuals under 50 with changing moles showed a higher yield of suspicious pigmented lesions, suggesting they may benefit from screening.