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Related Experiment Video

Updated: May 7, 2026

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
08:41

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Published on: August 13, 2019

Alveolar ridge preservation using resorbable bioactive ceramic composite: a histological study.

Mohanad Al-Sabbagh1, John Burt, Ahmed Barakat

  • 1USA.

Journal of the International Academy of Periodontology
|October 2, 2013
PubMed
Summary

Silica-calcium phosphate nanocomposite (SCPC) grafting in extraction sockets promotes new vital bone formation and reduces alveolar ridge dimensional changes. This bioactive graft material aids in preserving bone height and width for future dental implant placement.

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Area of Science:

  • Biomaterials Science
  • Oral and Maxillofacial Surgery
  • Regenerative Dentistry

Background:

  • Tooth extraction often leads to significant alveolar ridge resorption.
  • Preserving alveolar bone dimensions is crucial for successful dental implant placement.
  • Bioactive graft materials offer a potential solution for bone regeneration and dimensional stability.

Purpose of the Study:

  • To histologically evaluate new vital bone formation in extraction sockets grafted with silica-calcium phosphate nanocomposite (SCPC).
  • To assess the efficacy of SCPC in preserving alveolar ridge dimensions after tooth extraction.
  • To determine the suitability of SCPC as a bone graft material for subsequent dental implant procedures.

Main Methods:

  • Six patients with non-restorable maxillary central incisors underwent extraction and socket grafting with SCPC.

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Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
08:41

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Published on: August 13, 2019

Oral Biofilm Formation on Different Materials for Dental Implants
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Oral Biofilm Formation on Different Materials for Dental Implants

Published on: June 24, 2018

  • Bone core samples were retrieved after 6 months for histomorphometric analysis.
  • Alveolar bone height and width changes were assessed radiographically and clinically, respectively.

    • Main Results:

    • Histomorphometric analysis revealed 46.8% new vital bone and minimal residual graft material (2.5%) after 6 months.
    • Mean bone height resorption was 1.6 mm, and mean bone width resorption at the crest was 2 mm over the 6-month healing period.
    • These findings indicate successful bone regeneration and limited dimensional loss.

    Conclusions:

    • SCPC graft material effectively reduces alveolar ridge dimensional changes post-extraction.
    • SCPC facilitates the regeneration of new vital bone, supporting its use in socket preservation.
    • The study suggests SCPC is a promising material for enhancing bone regeneration and maintaining ridge integrity.