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Updated: May 7, 2026

Comprehensive Understanding of Inactivity-Induced Gait Alteration in Rodents
Published on: July 6, 2022
Changes of gait kinematics in different simulators of reduced gravity
Francesca Sylos-Labini1, Yuri P Ivanenko, Germana Cappellini
1a Laboratory of Neuromotor Physiology , Santa Lucia Foundation , Rome , Italy.
Abstract:
Gravity reduction affects the energetics and natural speed of walking and running. But, it is less clear how segmental coordination is altered. Various devices have been developed in the past to study locomotion in simulated reduced gravity. However, most of these devices unload only the body center of mass. The authors reduced the effective gravity acting on the stance or swing leg to 0.16g using different simulators. Locomotion under these conditions was associated with a reduction in the foot velocity and significant changes in angular motion. Moreover, when simulated reduced gravity directly affected the swing limb, it resulted in significantly slower swing and longer foot excursions, suggesting an important role of the swing phase dynamics in shaping locomotor patterns.
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