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Updated: May 7, 2026

Standard Membrane Feeding Assay for the Detection of Plasmodium falciparum Infection in Anopheles Mosquito Vectors
Published on: May 12, 2022
Malaria vector control in South Africa
B Brooke1, L Koekemoer, P Kruger
1Vector Control Reference Laboratory, Centre for Opportunistic, Tropical and Hospital Infections, National Institute for Communicable Diseases, Johannesburg, South Africa; Wits Research Institute for Malaria, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. maureenc@nicd.ac.za.
Insecticide resistance threatens malaria control. Indoor residual spraying (IRS) and insecticide-treated bednets (LLINs) are less effective, requiring increased investment in malaria control strategies for elimination.
Area of Science:
- Medical Entomology
- Public Health
- Tropical Medicine
Background:
- Malaria control heavily relies on insecticide-based interventions like indoor residual spraying (IRS) and long-lasting insecticide-treated bednets (LLINs).
- These methods have historically been effective but face challenges with widespread insecticide resistance in mosquito vectors.
- The diminishing susceptibility of vector populations to approved insecticides poses a significant threat to malaria control programs.
Purpose of the Study:
- To highlight the impact of increasing insecticide resistance on the efficacy of current malaria vector control methods.
- To emphasize the urgent need for increased resource allocation towards malaria control in South Africa.
Main Methods:
- This abstract does not detail specific methods but discusses the implications of existing research on insecticide resistance.
Main Results:
- Insecticide resistance in malaria vectors is increasingly undermining the effectiveness of IRS and LLINs.
- Few regions in Africa maintain mosquito populations susceptible to commonly used insecticides.
- Current vector control strategies are becoming less viable due to resistance.
Conclusions:
- Malaria elimination efforts are severely hampered by widespread insecticide resistance.
- South Africa must significantly increase investment in malaria control to overcome this challenge.
- Alternative or supplementary control strategies may be necessary to combat resistant vector populations.

